Pt. Mohan Shyam Sharma represents two gharanas: Nathdwara gharana and Bitia gharana. His Guru, Pandit Totaram Sharma too learnt from two gharanas. First, he trained under Pandit Murlidhar Sharma of the Kudau Singh gharana and then under Pandit Purushottam Das, the pioneer of the Nathdwara gharana. The Kudau Singh gharana is also known as the Bitia gharana and is the oldest school of pakhawaj playing.
He also had the opportunity of learning pakhawaj from Pandit Prem Vallabh, disciple of the legend, Ustad Ahmedjan Thirakwa. Consequently, Pandit ji has came to this confluence of two streams.

Pt. Mohan Shyam Sharma is a frequent performer and artist of All India Radio . He started his career as an accompanist with the Junior Dagar Brothers then toured with  Ustad Asad Ali Khan, Ustad Zia Mohiuddin Dagar and all the Dagars extensively in India and abroad. He is a much sought-after accompanist for all the most eminent exponents of dhrupad, vocal and instrumental indian classical musicians. He also accompanied Darbhanga gharana exponents, Pandit Vidhur Malika and Pandit Siya Ram Tiwari and accompanied world famous musicians of other styles as well including Pandit Ravi Shankar, Pandit Hari Prasad Chaurasia, and Kishori Amonkar.